Science

C. Neoformans Cryptococcosis in Myeloma Treatment

Monoklonale antistoffer har dukket opp som en hjørnestein i behandlingen av myelomatose. Darzalex (daratumumab), et humant IgG1κ monoklonalt antistoff, retter seg mot CD38, et glykoprotein sterkt uttrykt på myelomceller. Dette terapeutiske middelet har forvandlet myelombehandlingsparadigmer, og viser effektivitet i både monoterapi- og kombinasjonsregimer. Dens anvendelse representerer et betydelig sprang i å håndtere denne komplekse hematologiske …

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Super P Force: A Comprehensive Insight

Super P Force stands out in the pharmaceutical market as a dual-action medication. It tackles both erectile dysfunction (ED) and premature ejaculation (PE). The formulation combines sildenafil citrate 100 mg with dapoxetine 60 mg. Sildenafil, a PDE-5 inhibitor, promotes blood flow to the penis. Dapoxetine, a selective serotonin reuptake inhibitor (SSRI), increases serotonin levels. This …

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Motorfordonsskador och behandling av pediatrisk allergisk konjunktivit

Sökandet efter effektiva behandlingar vid pediatrisk allergisk konjunktivit förblir en central strävan inom oftalmologi. Att ta itu med denna sjukdom hos barn kräver noggrant övervägande av effektivitet, säkerhet och tolerabilitet. Alocril har dykt upp som ett lovande alternativ för att hantera symtom hos unga patienter. Att förstå dess roll och fördelar är avgörande för att …

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Zespół Landau-Kleffnera: Spostrzeżenia dotyczące badań neurofarmakologicznych

Ostatnie postępy w neurofarmakologii poszerzyły zakres interwencji terapeutycznych. Postępy te ułatwiły wgląd w zaburzenia neurologiczne, w tym zespół Landau-Kleffnera (LKS). Głębokie zrozumienie tych postępów wymaga zbadania modulacyjnej roli związków, takich jak dekstrorfan . Związek ten zyskuje na uwadze ze względu na swój potencjał w leczeniu różnych schorzeń nerwowych. Ponadto zaangażowanie innych dziedzin, takich jak kiła …

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دواء أرالين 250 مجم: استخدامات أقراص فوسفات الكلوروكين 250 مجم

يظل عقار فوسفات الكلوروكين 250 مجم، المعروف باسم Generic Aralen، محوريًا في إدارة الملاريا. يتم وصفه للوقاية والعلاج، وتمتد فعاليته إلى سلالات مختلفة من المتصورة. يتلقى المرضى المسافرون إلى المناطق الموبوءة هذا الدواء كإجراء وقائي. يتداخل عقار فوسفات الكلوروكين 250 مجم مع دورة نمو الطفيلي، مما يوقف تكاثره. يقلل هذا الانقطاع بشكل فعال من شدة …

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Effectiveness of carboxytherapy in the treatment of cellulite in healthy women: a pilot study

Carbon dioxide therapy, better known as carboxytherapy, relates to percutaneous infusion of medical carbon dioxide with therapeutic approaches, and its use in the treatment of localized fat has demonstrated good results. Gynoid lipodystrophy, also known as cellulite, affects 80%–90% of women after puberty, especially in the buttocks and thighs. Its etiology is complex and involves …

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[Carbon dioxide inhibits the generation of active forms of oxygen in human and animal cells and the significance of the phenomenon in biology and medicine]

Abstract Carbon dioxide (CO2) influence in generation of active oxygen forms (AOF) in human mononuclear cells (blood phagocytes and alveolar macrophages) and animal cells (tissue phagocytes, parenchymal and interstitial cells of liver, kidney, lung, brain, and stomach) was investigated. The AOF generation was examined by the methods of chemiluminescence (CL) using luminol, lucigenin, and NBT …

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Protective role of carbon dioxide (CO2) in generation of reactive oxygen species

Abstract The results testify to the fact that CO2 is a powerful inhibitor of reactive oxygen species (ROS) generation by cells (blood phagocytes and alveolar macrophages of 96 people and cells of inner organs and tissue phagocytes (of the liver, brain, myocardium, lungs, kidneys, stomach, and skeleton muscles), as well as by mitochondria of the …

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A novel system for transcutaneous application of carbon dioxide causing an “artificial Bohr effect” in the human body

Abstract Background: Carbon dioxide (CO(2)) therapy refers to the transcutaneous administration of CO(2) for therapeutic purposes. This effect has been explained by an increase in the pressure of O(2) in tissues known as the Bohr effect. However, there have been no reports investigating the oxygen dissociation of hemoglobin (Hb) during the transcutaneous application of CO(2)in vivo. …

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A Prospective Clinical and Instrumental Study on the Effects of a Transcutaneous Cosmeceutical Gel that is Claimed to Produce CO₂

Abstract Carboxytherapy is the therapeutic use of carbon dioxide (CO2) in its gaseous state. Since 1933, carboxytherapy has referred to either the subcutaneous injection of CO2 or percutaneous application in a warm bath. The present clinical study was performed to determine if there were any changes in the dermis after the application of a transcutaneous …

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